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Processes implemented
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Transform your vision into reality.
InnoSyn specializes in custom synthesis and process optimization for various chemical industries, providing tailored solutions for efficient production and high-quality compounds.
Transforming challenges into solutions.
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Our products are designed to elevate your business. From cutting-edge technologies to innovative solutions, we offer a range of tools that enhance efficiency, drive growth, and ensure compliance. Experience unmatched quality and performance with products tailored to meet your unique needs. Discover how our offerings can transform your operations and lead you to success!
Recombinant Pig Liver Esterase (PLE)
Hydroxynitrile lyases (HNL)
Glucose Dehydrogenase (GDH-01)
From Lab Procedure to Industrial Reality: Continuous Flow DIBAL-H Reduction of Esters to Aldehydes
This case study explores the selective partial reduction of esters to aldehydes, a process known for its challenges due to fast reaction kinetics, high exothermicity, and unstable intermediates. Traditional batch methods demand stringent temperature control and slow dosing of DIBAL-H at cryogenic conditions (-70 to -50 ºC), often resulting in over-reduction to alcohols. Here, we present a pilot-scale solution using continuous flow chemistry, achieving outputs of 0.72–1.2 kg/h. By incorporating 3D metal printing for flow reactors, heat exchangers, and static mixers, we demonstrate a scalable and efficient approach to managing this highly reactive process.
Aerobic Alcohol Oxidations from Lab-Scale to Industrial Implementation: Batch or Flow?
This case study examines aerobic alcohol oxidations using nitroxyl radicals like TEMPO and keto-ABNO, highlighting their efficiency and eco-friendliness. Continuous flow reactors excel in safety and scalability, achieving 96% yield for primary alcohols in under 5 minutes. However, batch reactors prove advantageous for secondary alcohols due to catalyst stability, showcasing the complementary benefits of both approaches.
Case Study: Viedma ripening for Naproxen
Obtaining enantiopure compounds from a racemic mixture without any additional chiral reagent. Not a dream, but a new reality. By using racemizing conditions and specific crystallization behavior the solid phase of a racemic mixture can be fully converted into the enantiomerically.
Latest News
Stay updated on our latest innovations, updates, and insights through the InnoSyn newsroom.
WO2026002830 - A Scalable Process for the Manufacture of 2,2-Bis(Aminomethyl)Propane-1,3-Diamine Tetrahydrochloride
InnoSyn Inventors: HERMSEN, Petrus and DIELEMANS, Hubertus
Process Development and Scale-Up of a Novel Route to 8-Aminooctanoic Acid
The development of robust and scalable synthetic routes remains a critical challenge in modern process chemistry, particularly when transitioning from laboratory concepts to industrial production.
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