Go Green with Biocatalysis: Sustainable Paths to Natural Solutions
Biocatalysis uses enzymes or microbial cells as catalysts for chemical synthesis. Biocatalysts are frequently inherently more selective than conventional chemical approaches (chemo-, regio- and enantioselectivity).
Biocatalysis employs enzymes as they are provided by nature and/or are improved in the laboratory as catalysts for challenging chemical reactions. Biocatalysis operates on the interface of biology and chemistry, making the integration of both disciplines in one team indispensable, like we do at InnoSyn.
Typically, biocatalysis is not just replacing a chemical step in a process by an enzymatic one, but enables shortcuts from alternative starting materials or process intermediates. This way shorter and more cost-efficient synthesis routes and chemical processes are possible.
Fast identification of suitable enzymes for novel products or new routes to existing products is achieved by efficient enzyme screening of thousands of enzymes available “off the shelf” for all synthetically useful enzyme classes, including HNL. This is followed by systematic experimentation to identify, improve, and optimize the biocatalytic reactions. Lastly, we provide fast and independent enzyme production and application of immobilized enzymes for scalable fermentation and chemical processes.
Biocatalysis Services
Enzymes and Biocatalytic reaction types
Oxidoreductases
- Oxidations
- Hydroxylations
- Reductive Aminations
Transferases
- Transaminations
- Phosphorylations
- Glycosylations
Hydrolases
- Ester synthesis and hydrolysis
- Amide synthesis and hydrolysis
- Nitrile hydrolysis
- Dehalogenations
- Deaminations
Lyases
- Carbon-carbon bond formation (aldolases & HNLs)
- Decarboxylations (amino and keto acid decarboxylases)
- Ammonia additions
- Water additions (esp. oleate and fatty acid hydratases)
Isomerases
- Racemisations
- Epimerisations
Ligases
- Esp. ATP-recycling for ligation reactions