Dr. Iwona Kaluzna joining the InnoSyn Management Team

It is our great pleasure to announce that per January 1st 2023, Iwona Kaluzna has been appointed as a new member of the Management Team of InnoSyn B.V....

10 January, 2023

Macrocyclic Baeyer-Villiger monooxygenase oxidation of cyclopentadecanone on 1 L scale

In the last couple of years our Biocatalysis team at @InnoSyn was very active in the development and scale up of numerous biocatalytic oxidation processes. As one reaction example here is a detailed process description of the Baeyer-Villiger...

26 September, 2022

Expanding the Toolbox of R-Selective Amine Transaminases by Identification and Characterization of New Members

“Expanding the Toolbox! New transaminases for the production of chiral and functional amines. The latest publication co-authored by us and our long-lasting collaboration Partners at ACIB and TU Graz....

26 September, 2022

Enzymatic Supply and Recycling of High-value Co-substrates and Co-factors for Industrial Biocatalysis

Enzymes catalysis an astonishing variety of chemistries and for this reason are applied as biocatalysts in chemical processes...

14 July, 2022

Development of a scalable synthesis of boronate β-lactamase inhibitors

Cost-effective and scalable production of the β-lactamase inhibitor by utilization two key steps: nickel-catalyzed boron insertion followed by enantioselective cyclopropanation resulting in the final cyclic product formation. Check it out!...

15 June, 2022

Counteracting Enantiospecific Behavior of Tailor-Made Additives During Chiral Symmetry Breaking: Growth Inhibition versus Solid-Solution Formation

Tailor-made additives strongly influence the outcome of a crystallization process. With a single chiral additive the symmetry breaking during Viedma ripening can be directed to either enantiomer at will...

24 May, 2022

Continuous Flow Technology as a game changer in Process R&D

Flow technology is one of the platforms to realize process intensification. Today, we see that next to intensifying chemical processes, flow technology intensifies the process development....

20 April, 2022

Teaser EUGO vanillin paper

This article on producing #vanillin in clean enzymatic reactions by oxidation of vanillyl alcohol with pure oxygen results from a very fruitful collaboration of us (#InnoSyn) with the researchers of the Autonomous University of Barcelona (UAB) in the framework of the EU project #ROBOX on...

04 April, 2022

New Enabling Chiral Crystallization Technologies – Transformation of Racemates into Pure Enantiomers

In recent years a renaissance in chiral crystallization technologies has enabled the complete deracemization of chiral compounds....

28 March, 2022

Sunlight fueled chemistry

As a society, we are currently facing two major challenges: the safeguarding of our future energy supply by the transfer from fossil fuels to sustainable energy sources, and, the reduction of emission of the greenhouse gas CO2....

07 February, 2022